You know the scripted sequence that happens where you enter the big security room with the heavy containment on/off lock switch? The one where SCP-049 comes in and you have to hide? Well as soon as SCP-049 enters the room and walks into the part of the room with the monitors, the game immediately crashes and I get a "SCP Containment Breach (1.3.7).exe has stopped working" message. Anyone else get this issue or know a fix? I cannot progress any further

You may need the 4gb patch update. It's a simple patch that changes the memory capacity of your game for X64 OS. https://undertowgames.com/forum/viewtopic.php?t=6498