I encountered additional issues with the newest version:

- As I tried to enter SCP-079's area, the game crashed, because it wasn't able to load the proper sfx for the AI (error message something like "failed to load sound sfx ai")

- Am I correct that the new versions (1.0 and 1.01) have much higher requirements to my main memory? I had several windows messages that my memory (4GB) is full because of SCP:CB

I have the same problems with sounds. Its not only in SCP-079's room. I had this bug in the pocket dimenshion.

I think it might mean you need a better PC to run this.
I've been to both those places without problem in both v 1.00 and 1.01

i have a problem where when i try to run the launcher i get an error saying

Failed to load Sound:SFX\button.ogg

and then the launcher shuts down

Try 1.0.4, unless you've already tried that version, which basically means YIKES. And yeah the 1.0 versions require more memory now. There seems to be no way to fix that. At a desperate move perhaps you could try compatibility with Windows 7 or XP or something, or run it as Administrator? I dunno in this case what's happening.